Drive down depression related costs and improve clinical outcomes

The high burden of depression is the leading cause of disability worldwide, and in many countries, treatment of mental health is one of the costliest areas of health care.1 Research shows, by adding deprexis® to existing treatment, total payments can be reduced by up to 32%.2


A Treatment You Can Trust

A CE-marked medical device, deprexis® is a safe and effective supplemental treatment for patients. Across more than a dozen trials, deprexis® has achieved effects that resemble traditional evidence-based depression treatments, such as cognitive behavioral therapy. 2,3,4

Easy Integration

deprexis®’ fully automated, AI-powered technology allows it to be easily integrated into any existing care plan. deprexis® can also be accessed through all devices with internet capabilities, allowing patients to self-manage their depression anytime, anywhere, in the available language most convenient to them.

Significant Reduction in Total Payments

Research shows adding deprexis® to existing treatment can result in an average of up to 34% reduction in total payments.2 That’s because deprexis® does not require additional coaching or extra physician time or capacity. Patients can achieve the positive effects independently.

Better Deployment of Targeted Support to Specific Patient Groups

GAIA, the company that developed and operates deprexis®, has produced numerous digital treatments supported by solid scientific evidence. Partnering with GAIA can help payers deploy these effective interventions to specific patient groups.

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Real Science, Real Evidence

RCTs demonstrate deprexis®’ effectiveness, safety and suitability.

Effective Depression Treatment

Nine independent studies conducted with deprexis® have demonstrated its effectiveness and have confirmed the increase in benefits when deprexis® is added to existing care plans.

Bonnet et al. (2018) Zwerenz et al. (2017) Berger et al. (2017) Beevers et al. (2017) Klein et al. (2016) Meyer et al. (2015) Moritz et al. (2012) Berger et al. (2011) Meyer et al. (2009)

Effective Treatment of Comorbid Depression

Depression is especially prevalent in patients with severe medical conditions and disorders. deprexis® has been shown to effectively treat depression as a comorbidity of epilepsy, multiple sclerosis and gambling disorder.

Bücker et al. (2018) Fischer et al. (2015) Schröder et al. (2014)

Proven Cost Reduction

A study of 3,805 participants demonstrated using deprexis® significantly reduces the cost of treating depression for health insurers, while simultaneously reducing depressive symptoms and increasing quality of life in patients.

Gräfe et al. (2020)

Scientifically Replicated

Multiple meta-analyses and systematic reviews have confirmed the scientific evidence gathered in 13 RCTs that deprexis® is an effective treatment for depression.

Twomey et al. (2020) Rogers et al. (2017) Karyotaki et al. (2017) Johansson & Andersson (2012) Richards & Richardson (2012) Cuijpers et al. (2011)

Medical Research Network

USA: University of Texas, Austin; Cedars Sinai Medical Center Los Angeles; University of Massachusetts Medical School

SWEDEN: The Karolinska Institute; Linkoping University

GERMANY: Universitätsklinikum Hamburg-Eppendorf (UKE); Charite Universitätsmedizin Berlin; Universität Trier; Universität Tübingen

UK: University of Cambridge; Kings College London; City University, London

FUNDING PARTNERS: the U.S. department of veteran affairs, the U.S. national multiple sclerosis society, the European Union, the European Commission, the German ministry of health, and the Brain and Behavior Research Foundation, the German Association of Psychotherapists (DPTV), major German health insurance companies and several other research centers, universities and hospitals across Europe, the U.S. and other regions.

Interested in deprexis®?